CBD as a Promising Treatment for Epilepsy: How Cannabidiol Can Help Manage Seizures

Author: Eva Keller

The use of cannabidiol (CBD) in treating epilepsy is gaining attention in the medical field. Epilepsy, a neurological disorder affecting millions worldwide, can significantly impact patients' quality of life. CBD has shown potential in reducing both the frequency and intensity of epileptic seizures, particularly in patients who do not find relief from conventional treatments. Studies suggest that CBD may have anticonvulsant effects and help regulate electrical activity in the brain. Discover how CBD can be used in the treatment of epilepsy and learn from our experience.

How Does CBD Help Fight Epilepsy?

CBD is a non-psychoactive cannabinoid that interacts with the endocannabinoid system (ECS) in the human body. This interaction triggers effects that can improve symptoms in epilepsy patients. Here are the primary mechanisms through which CBD combats epilepsy:

  • Anticonvulsant Properties: CBD has been found to reduce seizures by stabilizing electrical activity in the brain.
  • Neuroprotective Effects: CBD offers protective effects on the nervous system, which can be beneficial for individuals with epilepsy.

Key Findings from Studies:

  • Impact on GABA Levels: CBD affects gamma-aminobutyric acid (GABA) levels, which are often low in individuals with epilepsy. By reducing the absorption of GABA, CBD helps increase its levels in the brain, thereby reducing seizures.
  • Stabilization of Ion Channels: CBD stabilizes the function of ion channels in the body, similar to some antiepileptic drugs. Proper ion channel function is crucial for tissue and organ health.
  • Enhanced Drug Efficacy: CBD alters how nerve cells in the brain communicate, potentially increasing the effectiveness of other epilepsy medications.
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Epidiolex: The FDA-Approved CBD-Based Epilepsy Medication

Did you know there is an FDA-approved CBD-based medication for epilepsy in children? Epidiolex is a prescription medication used to treat two rare forms of epilepsy in children under the age of 2: Dravet syndrome and Lennox-Gastaut syndrome.

How to Dose CBD for Epilepsy

Based on our experience in hemp counseling over the last 10 years, the recommended daily dose of CBD for epilepsy is as follows:

  • General Dosage: If you cannot determine the timing of your seizures, start with 10% CBD oil twice a day. For children, begin with 5% CBD oil and gradually increase the dose. Start with 1 drop twice a day and increase the dosage every few days until the desired effect is achieved.
  • Timing-Based Dosage: If seizures occur at specific times of the day, concentrate the dosage around these times. Apply CBD about an hour before the expected seizures.
  • Night-Time Seizures: If seizures primarily occur at night, take 10% CBD oil before bed and in the morning after waking up.
  • During an Attack: If a seizure occurs, apply the entire daily dose of CBD between the lip and gums, massaging it into the gums with circular movements.

How Long Does It Take for CBD to Work in Epilepsy Treatment?

The time it takes for CBD to show effects in epilepsy treatment can vary depending on several factors:

  • Type of Epilepsy: Different types of epilepsy may respond differently to CBD. Some forms may be more sensitive to CBD's effects.
  • CBD Dosage: The effect of CBD can be dose-dependent. Higher doses may be required for some patients to achieve the desired therapeutic effect.
  • Individual Variability: Each person’s unique biochemical and genetic factors can influence how quickly they respond to CBD treatment. Some may experience effects within days or weeks, while others may take longer.

Patience is key—allow a few days to fully assess the effects of CBD.

CBD vs. THC: Understanding the Difference in Epilepsy Treatment

The primary difference between CBD and THC is psychoactivity. CBD is non-psychoactive, while THC is psychoactive. THC is not recommended for epilepsy treatment as it can exacerbate symptoms, especially the frequency of seizures.

Taking CBD Alongside Epilepsy Medications

When taking CBD with epilepsy medications, maintain a minimum interval of 2 hours between antiepileptic drugs and CBD products. This prevents contraindications and ensures there is no reduction in the effectiveness of antiepileptic drugs.

Understanding the Clinical Picture of Epilepsy

Epileptic seizures vary in type. Patients may experience either major seizures (disturbed consciousness, convulsions) or minor seizures (brief, often unnoticed episodes). The International League Against Epilepsy classifies seizures into two main groups: partial (focal) and generalized.

  • Partial Seizures: These begin in a restricted area of the brain and are the most common in adulthood. They may spread and develop into more complex seizures, affecting consciousness and causing automatic, ineffective movements.
  • Generalized Seizures: These involve the entire cerebral cortex, resulting in immediate loss of consciousness. Types of generalized seizures include convulsions, absences, and myoclonic seizures.
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How Can Hemp Help Epileptics?

In theory, hemp is highly suitable for treating epilepsy, especially in severe cases where conventional medicine fails. CBD has long been recognized for its anticonvulsant properties, which have been demonstrated in animal experiments. Additionally, CBD offers neuroprotective benefits that may help counter epilepsy.

From Theory to Practice: Real-World Success Stories

Hemp has shown promise in treating epilepsy, particularly in cases where traditional medicine falls short. One notable case involved an eight-year-old girl who experienced over 150 seizures per day. Despite the bleak prognosis, she began consuming small, safe amounts of hemp oil daily. Her symptoms improved dramatically, and she now experiences no seizures.